Regulation of a Notch 3-Hes 1 Pathway and Protective Effect by a Tocopherol-Omega Alkanol Chain Derivative in Muscle Atrophy s

@inproceedings{Grabowiecki2014RegulationOA,
  title={Regulation of a Notch 3-Hes 1 Pathway and Protective Effect by a Tocopherol-Omega Alkanol Chain Derivative in Muscle Atrophy s},
  author={Yannick von Grabowiecki and Cynthia Licona and Lavinia Palamiuc and Paula Rato Abreu and Vania Vidimar and Djalil Coowar and Georg Mellitzer and Christian Gaiddon},
  year={2014}
}
Muscular atrophy, a physiopathologic process associated with severe human diseases such as amyotrophic lateral sclerosis (ALS) or cancer, has been linked to reactive oxygen species (ROS) production. The Notch pathway plays a role in muscle development and in muscle regeneration upon physical injury. In this study, we explored the possibility that the Notch pathway participates in the ROS-relatedmuscular atrophy occurring in cancerassociated cachexia and ALS. We also tested whether hybrid… CONTINUE READING

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SHOWING 1-10 OF 55 REFERENCES

Reactive Oxygen Species in Skeletal Muscle Signaling

  • Journal of signal transduction
  • 2012
VIEW 19 EXCERPTS
HIGHLY INFLUENTIAL

Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity.

  • Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie
  • 2009
VIEW 17 EXCERPTS
HIGHLY INFLUENTIAL