Regulation of Wnt5a expression in human mammary cells by protein kinase C activity and the cytoskeleton.

@article{Jnsson1998RegulationOW,
  title={Regulation of Wnt5a expression in human mammary cells by protein kinase C activity and the cytoskeleton.},
  author={Maria J{\"o}nsson and Kenneth Smith and A. L. Harris},
  journal={British Journal of Cancer},
  year={1998},
  volume={78},
  pages={430 - 438}
}
The Wnts can be classified into two classes based on their ability to transform cells. The Wnt5a class can antagonize the effects of transforming Wnts partly through effects on cell migration. To understand the mechanisms of regulation of Wnt5a, we investigated its expression in human normal and breast cancer cell lines. Elevation of Wnt5a in HB2, a normal… CONTINUE READING