Regulation of Vitamin D Metabolism: The Kidney as an Endocrine Organ

@inproceedings{DeLuca1979RegulationOV,
  title={Regulation of Vitamin D Metabolism: The Kidney as an Endocrine Organ},
  author={Hector F DeLuca},
  year={1979}
}
By biological assay it was learned prior to the isolation and identification of 25-OH-D3 that its production (then termed peak IV) could be increased by increasing to high levels the dosage of vitamin D given to pigs (Blunt et al., 1968a). By increasing the dietary intake of vitamin D from 90 units of antirachitic activity per pound to 250,000 units per pound of feed, the amount of circulating peak IV metabolite could be increased from 1 unit/ml to 12 units/ml. However, it is self-evident that… CONTINUE READING

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