Regulation of Vitamin C Homeostasis during Deficiency

  title={Regulation of Vitamin C Homeostasis during Deficiency},
  author={Maiken Marie Lindblad and Pernille Tveden-Nyborg and Jens Lykkesfeldt},
Large cross-sectional population studies confirm that vitamin C deficiency is common in humans, affecting 5%-10% of adults in the industrialized world. Moreover, significant associations between poor vitamin C status and increased morbidity and mortality have consistently been observed. However, the absorption, distribution and elimination kinetics of vitamin C in vivo are highly complex, due to dose-dependent non-linearity, and the specific regulatory mechanisms are not fully understood… CONTINUE READING
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