Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

@article{Sonenberg2009RegulationOT,
  title={Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets},
  author={N. Sonenberg and A. Hinnebusch},
  journal={Cell},
  year={2009},
  volume={136},
  pages={731-745}
}
Translational control in eukaryotic cells is critical for gene regulation during nutrient deprivation and stress, development and differentiation, nervous system function, aging, and disease. We describe recent advances in our understanding of the molecular structures and biochemical functions of the translation initiation machinery and summarize key strategies that mediate general or gene-specific translational control, particularly in mammalian systems. 
The mechanism of eukaryotic translation initiation and principles of its regulation
Translational control in cellular and developmental processes
A mechanistic overview of translation initiation in eukaryotes
Function and Evolution of Upstream ORFs in Eukaryotes.
Redox Regulation of Cytosolic Translation in Plants.
Ribosome profiling and dynamic regulation of translation in mammals.
Regulation of mRNA translation by signaling pathways.
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