Regulation of Thyrotropin Physiology during Aging

  title={Regulation of Thyrotropin Physiology during Aging},
  author={Robert I. Gregerman},
The relationship of age to the functional state of the hypothalamic-pituitary-thyroid axis has been studied in a variety of ways to both animals and man. Basal concentrations of pituitary and of blood thyrotropin (TSH) have been measured and attempts made to relate these to circulating concentrations of the thyroid hormones. Thyrotropin-releasing hormone (TRH) has been administered to provoke pituitary secretion of TSH. The immunologic and functional characteristics of pituitary and blood TSH… CONTINUE READING

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