Regulation of Stat3 nuclear export.

@article{Bhattacharya2003RegulationOS,
  title={Regulation of Stat3 nuclear export.},
  author={Samita Bhattacharya and Christian Franz Wilfried Schindler},
  journal={The Journal of clinical investigation},
  year={2003},
  volume={111 4},
  pages={
          553-9
        }
}
Stat3 is the most pleiotropic member of the signal transducer and activator of transcription (STAT) family of transcription factors and mediates pivotal responses for the cytokine family. In resting cells, STATs, including Stat3, reside largely in the cytoplasm. Upon cytokine stimulation, they rapidly translocate to the nucleus, where they promote the expression of target genes. During the subsequent period of signal decay they are re-exported back to the cytoplasm in preparation for the next… CONTINUE READING

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 76 CITATIONS, ESTIMATED 63% COVERAGE

Crif1 is a novel transcriptional coactivator of STAT3.

  • The EMBO journal
  • 2008
VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2004
2019

CITATION STATISTICS

  • 11 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 40 REFERENCES

A Stat3-interacting protein (StIP1) regulates cytokine signal transduction.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2000
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Nucleocytoplasmic translocation of Stat1 is regulated by a leucine-rich export signal in the coiled-coil domain.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2000
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

Argi - nine / lysine - rich nuclear localization signals mediate interactions between dimeric STATs and importin - alpha 5

K. M. McBride, C. McDonald, N. C. Reich
  • J . Biol . Chem .
  • 2002

Identification of a nuclear Stat1 protein tyrosine phosphatase

J ten Hoeve
  • Mol. Cell Biol
  • 2002
VIEW 1 EXCERPT