Regulation of Salmonella-induced neutrophil transmigration by epithelial ADP-ribosylation factor 6.

@article{Criss2001RegulationOS,
  title={Regulation of Salmonella-induced neutrophil transmigration by epithelial ADP-ribosylation factor 6.},
  author={Alison K Criss and Milton Silva and James E. Casanova and Beth Ann McCormick},
  journal={The Journal of biological chemistry},
  year={2001},
  volume={276 51},
  pages={48431-9}
}
Salmonella typhimurium elicits an acute inflammatory response in the host intestinal epithelium, characterized by the movement of polymorphonuclear leukocytes (PMN) across the epithelial monolayer to the intestinal lumen. It was recently shown that SipA, a protein secreted by S. typhimurium, is necessary and sufficient to drive PMN transmigration across model intestinal epithelia (Lee, C. A., Silva, M., Siber, A. M., Kelly, A. J., Galyov, E., and McCormick, B. A. (2000) Proc. Natl. Acad Sci… CONTINUE READING

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