Regulation of Retinol-binding Protein Metabolism by Vitamin A Status in the Rat*

  • Published 2003


Retinol circulates in rat plasma bound to a specific protein, retinol-binding protein (RBP). A radioimmunoassay for rat RBP was developed with a double antibody precipitation technique. The immunoassay accurately measures RBP in amounts of 0.5 to 3 ng per assay tube. There was no significant difference in the immunoreactivity of apo-RBP as compared to holo… (More)


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