Regulation of Release of Hepatocyte Growth Factor From Human Promyelocytic Leukemia Cells, HL-60, by 1,25-Dihydroxyvitamin D,, 12-0-Tetradecanoylphorbol 13-Acetate, and Dibutyryl Cyclic Adenosine Monophosphate

Abstract

Hepatocyte growth factor (HGF) secreted from human promyelocytic leukemia cell line, HL-60, is indistinguishable from HGF in human plasma and its release is significantly stimulated by 1 2-0-tetradecanoylphorbol-I 3-acetate (TPA), a differentiation-inducer of HL-60 cells into monocytes/macrophages (Nishino T et al: Biochem Biophys Res Commun 181 :323, 1991… (More)

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