Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation.

@article{Jung2011RegulationOR,
  title={Regulation of RCAN1 protein activity by Dyrk1A protein-mediated phosphorylation.},
  author={Min-su Jung and Jung-Hwa Park and Young Shin Ryu and S. Choi and Song-Hee Yoon and Mi-Yang Kwen and Ji Youn Oh and Woo-Joo Song and Sul-Hee Chung},
  journal={The Journal of biological chemistry},
  year={2011},
  volume={286 46},
  pages={40401-12}
}
Two genes on chromosome 21, namely dual specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) and regulator of calcineurin 1 (RCAN1), have been implicated in some of the phenotypic characteristics of Down syndrome, including the early onset of Alzheimer disease. Although a link between Dyrk1A and RCAN1 and the nuclear factor of activated T cells (NFAT) pathway has been reported, it remains unclear whether Dyrk1A directly interacts with RCAN1. In the present study, Dyrk1A is shown to… CONTINUE READING
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Phosphorylation of RCAN1 by Dyrk1A NOVEMBER

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1 Excerpt

Phosphorylation of RCAN1 by Dyrk1A 40412 JOURNAL OF BIOLOGICAL CHEMISTRY VOLUME

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