Regulation of Pseudomonas quinolone signal synthesis in Pseudomonas aeruginosa.

@article{Wade2005RegulationOP,
  title={Regulation of Pseudomonas quinolone signal synthesis in Pseudomonas aeruginosa.},
  author={Dana S Wade and Michael Worth Calfee and Edson R Rocha and Elizabeth A Ling and Elana Engstrom and James Ph Coleman and Everett C Pesci},
  journal={Journal of bacteriology},
  year={2005},
  volume={187 13},
  pages={
          4372-80
        }
}
Pseudomonas aeruginosa is an opportunistic pathogen that causes chronic lung infections in cystic fibrosis patients and is a major source of nosocomial infections. This bacterium controls many virulence factors by using two quorum-sensing systems, las and rhl. The las system is composed of the LasR regulator protein and its cell-to-cell signal, N-(3-oxododecanoyl) homoserine lactone, and the rhl system is composed of RhlR and the signal N-butyryl homoserine lactone. A third intercellular signal… CONTINUE READING

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