Regulation of Programmed Ribosomal Frameshifting by Co-Translational Refolding RNA Hairpins

Abstract

RNA structures are unwound for decoding. In the process, they can pause the elongating ribosome for regulation. An example is the stimulation of -1 programmed ribosomal frameshifting, leading to 3' direction slippage of the reading-frame during elongation, by specific pseudoknot stimulators downstream of the frameshifting site. By investigating a recently… (More)
DOI: 10.1371/journal.pone.0062283

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