Regulation of PCNA–protein interactions for genome stability

@article{Mailand2013RegulationOP,
  title={Regulation of PCNA–protein interactions for genome stability},
  author={N. Mailand and Ian Gibbs-Seymour and S. Bekker-Jensen},
  journal={Nature Reviews Molecular Cell Biology},
  year={2013},
  volume={14},
  pages={269-282}
}
Proliferating cell nuclear antigen (PCNA) has a central role in promoting faithful DNA replication, providing a molecular platform that facilitates the myriad protein–protein and protein–DNA interactions that occur at the replication fork. Numerous PCNA-associated proteins compete for binding to a common surface on PCNA; hence these interactions need to be tightly regulated and coordinated to ensure proper chromosome replication and integrity. Control of PCNA–protein interactions is… Expand
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References

SHOWING 1-10 OF 158 REFERENCES
Tyrosine phosphorylation controls PCNA function through protein stability
Chk1 and Claspin potentiate PCNA ubiquitination.
...
1
2
3
4
5
...