Regulation of Oncogene Expression in T-DNA-Transformed Host Plant Cells

@inproceedings{Zhang2015RegulationOO,
  title={Regulation of Oncogene Expression in T-DNA-Transformed Host Plant Cells},
  author={Yi Zhang and Chil-Woo Lee and Nora Wehner and Fabian Imdahl and Veselova Svetlana and Christoph Weiste and Wolfgang Dr{\"o}ge-Laser and Rosalia Deeken},
  booktitle={PLoS pathogens},
  year={2015}
}
Virulent Agrobacterium tumefaciens strains integrate their T-DNA into the plant genome where the encoded agrobacterial oncogenes are expressed and cause crown gall disease. Essential for crown gall development are IaaH (indole-3-acetamide hydrolase), IaaM (tryptophan monooxygenase) and Ipt (isopentenyl transferase), which encode enzymes for the biosynthesis of auxin (IaaH, IaaM) and cytokinin (Ipt). Although these oncogenes are well studied as the tumor-inducing principle, nothing is known… CONTINUE READING
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