Regulation of Na(+)-K(+)-ATPase by cAMP-dependent protein kinase anchored on membrane via its anchoring protein.

@article{Kurihara2000RegulationON,
  title={Regulation of Na(+)-K(+)-ATPase by cAMP-dependent protein kinase anchored on membrane via its anchoring protein.},
  author={Kinji Kurihara and Nobuo Nakanishi and Takao Ueha},
  journal={American journal of physiology. Cell physiology},
  year={2000},
  volume={279 5},
  pages={
          C1516-27
        }
}
Na(+)-K(+)- ATPase alpha-subunits in basolateral membrane vesicles (BLMVs) purified from rat parotid glands were (32)P-labeled within 5 s by incubation with [gamma-(32)P]ATP at 37 degrees C in the presence of cAMP, but no labeling occurred without cAMP. Phosphorylation of Na(+)-K(+)-ATPase was associated with a decrease in its activity. This alpha-subunit phosphorylation disappeared when BLMVs were briefly incubated with cAMP and subsequent washing before the incubation with [gamma-(32)P]ATP… 

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Cyclic nucleotide phosphodiesterases.

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