Regulation of NF-κB signaling by caspases and MALT1 paracaspase

@article{Staal2011RegulationON,
  title={Regulation of NF-κB signaling by caspases and MALT1 paracaspase},
  author={Jens Staal and Tine Bekaert and Rudi Beyaert},
  journal={Cell Research},
  year={2011},
  volume={21},
  pages={40-54}
}
Caspases are intracellular proteases that are best known for their function in apoptosis signaling. It has become evident that many caspases also function in other signaling pathways that propagate cell proliferation and inflammation, but studies on the inflammatory function of caspases have mainly been limited to caspase-1-mediated cytokine processing. Emerging evidence, however, indicates an important contribution of caspases as mediators or regulators of nuclear factor-κB (NF-κB) signaling… CONTINUE READING

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