Regulation of Leishmania (L.) amazonensis Protein Expression by Host T Cell Dependent Responses: Differential Expression of Oligopeptidase B, Tryparedoxin Peroxidase and HSP70 Isoforms in Amastigotes Isolated from BALB/c and BALB/c Nude Mice

@inproceedings{Teixeira2015RegulationOL,
  title={Regulation of Leishmania (L.) amazonensis Protein Expression by Host T Cell Dependent Responses: Differential Expression of Oligopeptidase B, Tryparedoxin Peroxidase and HSP70 Isoforms in Amastigotes Isolated from BALB/c and BALB/c Nude Mice},
  author={Priscila Camillo Teixeira and Leonardo Garcia Velasquez and Ana Paula Lepique and Eloiza de Rezende and Jos{\'e} Matheus Camargo Bonatto and Marcello Andr{\'e} Barcinski and Edecio Cunha-Neto and Beatriz S Stolf},
  booktitle={PLoS neglected tropical diseases},
  year={2015}
}
Leishmaniasis is an important disease that affects 12 million people in 88 countries, with 2 million new cases every year. Leishmania amazonensis is an important agent in Brazil, leading to clinical forms varying from localized (LCL) to diffuse cutaneous leishmaniasis (DCL). One interesting issue rarely analyzed is how host immune response affects Leishmania phenotype and virulence. Aiming to study the effect of host immune system on Leishmania proteins we compared proteomes of amastigotes… CONTINUE READING
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