Regulation of KCNE1-dependent K+ current by the serum and glucocorticoid-inducible kinase (SGK) isoforms

@article{Embark2002RegulationOK,
  title={Regulation of KCNE1-dependent K+ current by the serum and glucocorticoid-inducible kinase (SGK) isoforms},
  author={Hamdy M. Embark and Christoph B{\"o}hmer and Volker Vallon and Friedrich C. Luft and Florian Lang},
  journal={Pfl{\"u}gers Archiv},
  year={2002},
  volume={445},
  pages={601-606}
}
The slowly activating K+ channel subunit KCNE1 is expressed in a variety of tissues including proximal renal tubules, cardiac myocytes and stria vascularis of inner ear. The present study has been performed to explore whether the serum- and glucocorticoid-inducible kinase family members SGK1, SGK2, or SGK3 and/or protein kinase B (PKB) influence K+ channel activity in Xenopus oocytes expressing KCNE1. cRNA encoding KCNE1 was injected with or without cRNA encoding wild-type SGK1, constitutively… 

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