Regulation of ICAM-1 expression in gingival fibroblasts infected with high-glucose-treated P. gingivalis.


Porphyromonas gingivalis is a major pathogen in the initiation and progression of periodontal disease, which is recognized as a common complication of diabetes. ICAM-1 expression by human gingival fibroblasts (HGFs) is crucial for regulating local inflammatory responses in inflamed periodontal tissues. However, the effect of P. gingivalis in a high-glucose… (More)
DOI: 10.1111/cmi.12146


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