Regulation of Hemolysin Expression and Virulence of Staphylococcus aureus by a Serine/Threonine Kinase and Phosphatase

Abstract

Exotoxins, including the hemolysins known as the alpha (alpha) and beta (beta) toxins, play an important role in the pathogenesis of Staphylococcus aureus infections. A random transposon library was screened for S. aureus mutants exhibiting altered hemolysin expression compared to wild type. Transposon insertions in 72 genes resulting in increased or… (More)
DOI: 10.1371/journal.pone.0011071

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@inproceedings{Burnside2010RegulationOH, title={Regulation of Hemolysin Expression and Virulence of Staphylococcus aureus by a Serine/Threonine Kinase and Phosphatase}, author={Kellie L. Burnside and Annalisa Lembo and Melissa de los Reyes and Anton B. Iliuk and Nguyen-Thao BinhTran and James E. Connelly and Wan-Jung Lin and Byron Z. Schmidt and Anthony R. Richardson and Ferric C Fang and Weiguo Andy Tao and Lakshmi Rajagopal}, booktitle={PloS one}, year={2010} }