Regulation of Hematopoietic Stem Cell Fate: Self-Renewal, Quiescence and Survival

@inproceedings{Kubota2012RegulationOH,
  title={Regulation of Hematopoietic Stem Cell Fate: Self-Renewal, Quiescence and Survival},
  author={Y. Kubota and Shinya Kimura},
  year={2012}
}
Hematopoietic stem cells (HSCs) are probably the most extensively characterized somatic stem cells and are the only stem cells that have been clinically used to treat diseases such as leukemia, germ cell tumors, and congenital immunodeficiencies. Because of their capacity for self-renewal and their ability to differentiate into different lineages, HSCs are able to continually replenish the cells that make up the hematopoietic system (Kondo et al., 2003). Decades of intensive study using… CONTINUE READING

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