Regulation of Gene Expression in Neurospora crassa with a Copper Responsive Promoter

  title={Regulation of Gene Expression in Neurospora crassa with a Copper Responsive Promoter},
  author={Teresa M. Lamb and Justin Vickery and Deborah Bell-Pedersen},
Precise control of gene expression is a powerful method to elucidate biological function, and protein overexpression is an important tool for industry and biochemistry. Expression of the Neurospora crassa tcu-1 gene (NCU00830), encoding a high-affinity copper transporter, is tightly controlled by copper availability. Excess copper represses, and copper depletion, via the use of a copper chelator, activates expression. The kinetics of induction and repression of tcu-1 are rapid, and the effects… CONTINUE READING
9 Citations
30 References
Similar Papers


Publications citing this paper.
Showing 1-9 of 9 extracted citations


Publications referenced by this paper.
Showing 1-10 of 30 references

Roles of putative HistoAsp signaling modules HPT1 and RRG2 , on viability and sensitivity to osmotic and oxidative stresses in Neurospora crassa

  • M. L. Shinohara, J. J. Loros, J. C. Dunlap
  • Curr . Genet .
  • 2007

A high - throughput gene knockout procedure for Neurospora reveals functions for multiple transcription factors

  • J. H. Kim
  • Proc . Natl . Acad . Sci . USA
  • 2006

Similar Papers

Loading similar papers…