Regulation of GPCR signaling in hypertension.

  title={Regulation of GPCR signaling in hypertension.},
  author={Henriette L Brinks and Andrea D. Eckhart},
  journal={Biochimica et biophysica acta},
  volume={1802 12},
Hypertension represents a complex, multifactorial disease and contributes to the major causes of morbidity and mortality in industrialized countries: ischemic and hypertensive heart disease, stroke, peripheral atherosclerosis and renal failure. Current pharmacological therapy of essential hypertension focuses on the regulation of vascular resistance by inhibition of hormones such as catecholamines and angiotensin II, blocking them from receptor activation. Interaction of G-protein coupled… CONTINUE READING


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  • J. S. Martini
  • Raake, L.E. Vinge, B.R. DeGeorge Jr., J.K…
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