Regulation of GABA transporter activity and mRNA expression by estrogen in rat preoptic area.

@article{Herbison1995RegulationOG,
  title={Regulation of GABA transporter activity and mRNA expression by estrogen in rat preoptic area.},
  author={Allan E Herbison and Sarah J. Augood and Sharon X Simonian and Carlene Chapman},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1995},
  volume={15 12},
  pages={8302-9}
}
This study has examined whether estrogen regulates GABA transporter synthesis and activity in the female rat brain. In the first experiment in situ hybridization studies examined the effects of ovariectomy on cellular GABA transporter-1 (GAT-1) mRNA content. A 25% decrease in GAT-1 mRNA expression was detected within the medial preoptic area (MPOA) but not the parietal cortex, magnocellular preoptic nucleus (Mg-POA) or caudate-putamen (C-P). Estrogen replacement for 7 d returned GAT-1 mRNA… CONTINUE READING

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References

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Showing 1-10 of 49 references

Cellular and molecular mechanisms of female reproductive behaviors

  • DW Pfaff, S Schwartz-Giblin, MM McCarthy, L Kow
  • 1994

Cellular and molecular mechanisms of female reproductive behaviors. In: The physiology of reproduction (Knobil E, Neil1

  • DW Pfaff, S Schwartz-Giblin, MM McCarthy, L Kow
  • JD, eds),
  • 1994
1 Excerpt

Maternal behavior. In: The physiology of reproduction (Knobil E, Neil1 JD eds), pp 221-284

  • M Numan
  • 1994
2 Excerpts

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