Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization.


With at least 1000 family members encoded by mammalian genomes, the G protein-coupled receptors (GPCRs) represent the most diverse group of signaling proteins known (Bockaert and Pin, 1999). GPCRs are involved in the regulation of a wide variety of physiological processes including, but not limited to, the sensory perceptions of pain, light, odors and… (More)


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