Regulation of Expression of Renal Organic Anion Transporters OAT1 and OAT3 in a Model of Ischemia/Reperfusion Injury.

@article{Preising2015RegulationOE,
  title={Regulation of Expression of Renal Organic Anion Transporters OAT1 and OAT3 in a Model of Ischemia/Reperfusion Injury.},
  author={Christina Preising and Reinhard Schneider and Michael Bucher and Michael Gekle and Christoph Sauvant},
  journal={Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology},
  year={2015},
  volume={37 1},
  pages={1-13}
}
BACKGROUND Recently, we gained evidence that impairment of rOat1 and rOat3 expression induced by ischemic acute kidney injury (AKI) is mediated by COX metabolites and this suppression might be critically involved in renal damage. METHODS (i) Basolateral organic anion uptake into proximal tubular cells after model ischemia and reperfusion (I/R) was… CONTINUE READING