Regulation of Epileptiform Discharges in Rat Neocortex by Hcn Channels 1 2

25 Hyperpolarization-activated, cyclic-nucleotide gated, non-specific cation (HCN) 26 channels have a well-characterized role in regulation of cellular excitability and network 27 activity. The role of these channels in control of epileptiform discharges is less 28 thoroughly understood. This is especially pertinent given altered HCN channel 29 expression… (More)