Regulation of Energy Homeostasis via GPR120

  title={Regulation of Energy Homeostasis via GPR120},
  author={Atsuhiko Ichimura and Takafumi Hara and Akira Hirasawa},
  booktitle={Front. Endocrinol.},
Free fatty acids (FFAs) are fundamental units of key nutrients. FFAs exert various biological functions, depending on the chain length and degree of desaturation. Recent studies have shown that several FFAs act as ligands of G-protein-coupled receptors (GPCRs), activate intracellular signaling and exert physiological functions via these GPCRs. GPR120 (also known as free fatty acid receptor 4) is activated by unsaturated medium- to long-chain FFAs and has a critical role in various physiological… CONTINUE READING
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