Regulation of E-cadherin/catenin complex patterns by epidermal growth factor receptor modulation in human lung cancer cells.

@article{Moustafa2002RegulationOE,
  title={Regulation of E-cadherin/catenin complex patterns by epidermal growth factor receptor modulation in human lung cancer cells.},
  author={Ala-Eddin Al Moustafa and Lily Yen and Naciba Benlimame and Moulay A. Alaoui-Jamali},
  journal={Lung cancer},
  year={2002},
  volume={37 1},
  pages={49-56}
}
We previously demonstrated that a ligand-blocking monoclonal antibody (mAb) against the epidermal growth factor-receptor (EGF-R), LA1, induced morphological conversion from epithelial-like to epithelial of the human lung cancer cell line, H322. This was accompanied by an up-regulation of epithelial cadherin (E-cadherin) expression (Clin. Cancer Res. 5 (1999… CONTINUE READING