Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion.

Abstract

Mucosal epithelial cell layers are constantly exposed to a complex resident microflora. Deleted in malignant brain tumors 1 (DMBT1) belongs to the group of secreted scavenger receptor cysteine-rich proteins and is considered to be involved in host defense by pathogen binding. This report describes the regulation and function of DMBT1 in intestinal… (More)

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@article{Rosenstiel2007RegulationOD, title={Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion.}, author={Philip Rosenstiel and Christian Sina and Caroline End and Marcus Renner and S. Sundar Kumar Lyer and Andreas Till and Stephan Hellmig and Susanna Nikolaus and Ulrich Robert Foelsch and Burkhard Maria Helmke and Frank Autschbach and Peter Schirmacher and Petra Kioschis and Mathias Hafner and Annemarie Poustka and Jan Mollenhauer and Stefan Schreiber}, journal={Journal of immunology}, year={2007}, volume={178 12}, pages={8203-11} }