Regulation of Caveolin-1 Expression Determines Early Brain Edema After Experimental Focal Cerebral Ischemia.

@article{Choi2016RegulationOC,
  title={Regulation of Caveolin-1 Expression Determines Early Brain Edema After Experimental Focal Cerebral Ischemia.},
  author={Kang-Ho Choi and H W Kim and M S Park and J T Kim and Ja-Hae Kim and Kyung-Ah Cho and M. C. M. Lee and Hong-Joon Lee and Ki-hyun Cho},
  journal={Stroke},
  year={2016},
  volume={47 5},
  pages={1336-43}
}
BACKGROUND AND PURPOSE Most patients with cerebral infarction die of brain edema because of the breakdown of the blood-brain barrier (BBB) in ischemic tissue. Caveolins (a group of proteins) are key modulators of vascular permeability; however, a direct role of caveolin-1 (Cav-1) in the regulation of BBB permeability during ischemic injury has yet to be identified. METHODS Cav-1 expression was measured by immunoblotting after photothrombotic ischemia. A direct functional role of Cav-1 in… CONTINUE READING
Highly Cited
This paper has 45 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Low-Dose Evans Blue Dye for Near-Infrared Fluorescence Imaging in Photothrombotic Stroke Model

International journal of medical sciences • 2018
View 5 Excerpts
Highly Influenced

Inflammatory mediator expression within retrieved clots in acute ischemic stroke

Annals of clinical and translational neurology • 2018
View 1 Excerpt

Photothrombotic Stroke as a Model of Ischemic Stroke

Translational Stroke Research • 2017
View 1 Excerpt

ZW800-1 for Assessment of Blood-Brain Barrier Disruption in a Photothrombotic Stroke Model

International journal of medical sciences • 2017
View 2 Excerpts

References

Publications referenced by this paper.
Showing 1-10 of 37 references

Similar Papers

Loading similar papers…