Regulation of Calcium-Permeable TRPV2 Channel by Insulin in Pancreatic β-Cells


OBJECTIVE Calcium-permeable cation channel TRPV2 is expressed in pancreatic beta-cells. We investigated regulation and function of TRPV2 in beta-cells. RESEARCH DESIGN AND METHODS Translocation of TRPV2 was assessed in MIN6 cells and cultured mouse beta-cells by transfecting TRPV2 fused to green fluorescent protein or TRPV2 containing c-Myc tag in the… (More)
DOI: 10.2337/db08-0862


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