Regulation of CCL20 expression in astrocytes by IL-6 and IL-17.

Abstract

Astrocytes have an important role in the regulation of inflammation within the central nervous system (CNS). In neuroinflammatory conditions such as multiple sclerosis, numerous cytokines and chemokines are elevated including IL-6, IL-17, and CCL20. IL-17 enhances IL-6 signaling and subsequent IL-6 expression in astrocytes. CCL20 is a CC motif chemokine… (More)
DOI: 10.1002/glia.22307

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Cite this paper

@article{Meares2012RegulationOC, title={Regulation of CCL20 expression in astrocytes by IL-6 and IL-17.}, author={Gordon P. Meares and Xiangyu Ma and Hongwei Qin and Etty Nadia Benveniste}, journal={Glia}, year={2012}, volume={60 5}, pages={771-81} }