Regulation of B cell proliferation and differentiation by retinoic acid.

  title={Regulation of B cell proliferation and differentiation by retinoic acid.},
  author={Ase Ertesv{\aa}g and Soheil Naderi and Heidi Kiil Blomhoff},
  journal={Seminars in immunology},
  volume={21 1},
Vitamin A protects against development of infectious diseases, and B cells are important players in this process. Keys to the protective role of retinoic acid (RA) against infections appear to be its ability to enhance antibody responses against T-cell dependent and independent type 2 antigens, as well as to locally stimulate IgA production in mucosal tissues. The elucidation of molecular mechanisms involved in RA-mediated regulation of proliferation and differentiation of B cells not only… CONTINUE READING
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