Regulation of ATR-dependent pathways by the FHA domain containing protein SNIP1

@article{Roche2007RegulationOA,
  title={Regulation of ATR-dependent pathways by the FHA domain containing protein SNIP1},
  author={Kevin C Roche and Sonia Rocha and Cameron P. Bracken and Neil D. Perkins},
  journal={Oncogene},
  year={2007},
  volume={26},
  pages={4523-4530}
}
The forkhead associated (FHA) domain-containing protein Smad nuclear interacting protein 1 (SNIP1) has multiple cellular functions, including the ability to interact with DNA-binding transcription factors and transcriptional coactivators. Moreover, we have demonstrated previously that SNIP1 regulates cyclin D1 expression and promoter activity. Here, we identify a new function for SNIP1 as a regulator of ATR checkpoint kinase-dependent pathways in human U-2 OS osteosarcoma cells: SNIP1 is… CONTINUE READING
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