Regulation of ACV synthetase activity in the beta-lactam biosynthetic pathway by carbon sources and their metabolites

@article{Zhang2004RegulationOA,
  title={Regulation of ACV synthetase activity in the beta-lactam biosynthetic pathway by carbon sources and their metabolites},
  author={Jinyou Zhang and Arnold L. Demain},
  journal={Archives of Microbiology},
  year={2004},
  volume={158},
  pages={364-369}
}
The activity of δ-l-α-aminoadipyl)-l-cysteinyl-d-valine catalysis. Addition of l-cysteine to fermentation media increased β-lactam production in both organisms and alleviated the negative carbon source regulation by glycerol in S. clavuligerus.