Regulation of ACE gene expression and plasma levels during rat postnatal development.

@article{Costerousse1994RegulationOA,
  title={Regulation of ACE gene expression and plasma levels during rat postnatal development.},
  author={Olivier Costerousse and Jacqueline Allegrini and Huaming Huang and J Bounhik and François Alhenc-G{\'e}las},
  journal={The American journal of physiology},
  year={1994},
  volume={267 5 Pt 1},
  pages={
          E745-53
        }
}
Angiotensin I-converting enzyme (kininase II, ACE) is a transmembrane ectoenzyme of vascular endothelial cells that is also secreted in plasma. To understand why plasma ACE levels are elevated in children compared with adults, the age-related changes in ACE mRNA and enzyme levels were studied in 1-day- to 3-mo-old rats. In the lung, a rich source of endothelial ACE, the abundance of ACE mRNA and the microsomal ACE concentration increased progressively and tripled during the first 3 mo. This… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 25 CITATIONS

Similar Papers

Loading similar papers…