Regulation of 2-5 A phosphodiesterase activity by cAMP-dependent phosphorylation: mechanism and biological role.

Abstract

The results of the present study permit the explanation of one of the mechanisms of the interconnection between the regulatory systems of cAMP and 2-5A. cAMP-dependent regulation of 2'-PDE was found to involve phosphorylation of the specific protein inhibitor. Originally, a similar way of regulation of the enzyme activity was discovered for protein… (More)

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@article{Severin1985RegulationO2, title={Regulation of 2-5 A phosphodiesterase activity by cAMP-dependent phosphorylation: mechanism and biological role.}, author={Evgeny S Severin and Alexander V. Itkes and Olga N. Kartasheva and Vera L. Tunitskaya and Kyril T. Turpaev and C A Kafiani}, journal={Advances in enzyme regulation}, year={1985}, volume={23}, pages={365-76} }