• DOI:10.4236/IJCM.2012.34051
Corpus ID: 21151975

Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 and 2 in Rheumatoid Arthritis

@article{Beyeler2012RegulationO1,
  title={Regulation of 11β-Hydroxysteroid Dehydrogenase Type 1 and 2 in Rheumatoid Arthritis},
  author={C. Beyeler and B. Dick and H. Bird and B. Frey},
  journal={International Journal of Physical Medicine and Rehabilitation},
  year={2012},
  volume={2012},
  pages={254-262}
}

• C. Beyeler, B. Dick, +1 author B. Frey
• Published 2012
• Medicine
• International Journal of Physical Medicine and Rehabilitation

Objective. The sequential activities of the 11β-hydroxysteroid dehydrogenase enzymes type 1 and 2 have not been investigated so far in patients suffering from rheumatoid arthritis before and after starting treatment though the enzymes balancing cortisol and cortisone levels are involved in regulating various inflammatory diseases. Methods. In a retrospective study, a panel of 41 urinary steroid metabolites has been analysed in a group of 18 patients with active rheumatoid arthritis (RA) as they… Expand

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