Regulation of 1-alpha, 25-dihydroxyvitamin D3 on interleukin-6 and interleukin-8 induced by sulfur mustard (HD) on human skin cells.

@article{Arroyo2003RegulationO1,
  title={Regulation of 1-alpha, 25-dihydroxyvitamin D3 on interleukin-6 and interleukin-8 induced by sulfur mustard (HD) on human skin cells.},
  author={Carmen M Arroyo and Robert K. Kan and Damon L Burman and David W. Kahler and Marian R. Nelson and Charlene M. Corun and Juanita J Guzman and Clarence A. Broomfield},
  journal={Pharmacology & toxicology},
  year={2003},
  volume={92 5},
  pages={204-13}
}
The regulatory effects of the active form of vitamin D, 1-alpha, 25-dihydroxyvitamin D3 (1-alpha, 25 (OH)2D3) were assessed on the cytokine and chemokine secretion induced by sulfur mustard on human skin fibroblasts and human epidermal keratinocytes. Stimulation of human skin fibroblasts with sulfur mustard (10(-4) M for 24 hr at 37 degrees ) resulted in approximately a 5 times increase in the secretion of interleukin-6 and over a 10 times increase for interleukin-8, which was inhibited by 1… CONTINUE READING

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The regulatory effects of the active form of vitamin D , 1-alpha , 25-dihydroxyvitamin D3 ( 1-alpha , 25 ( OH)2D3 ) were assessed on the cytokine and chemokine secretion induced by sulfur mustard on human skin fibroblasts and human epidermal keratinocytes .
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