Regulation by mitophagy.

  title={Regulation by mitophagy.},
  author={Nobutaka Hattori and Shinji Saiki and Yuzuru Imai},
  journal={The international journal of biochemistry & cell biology},
Eukaryotes employ elaborate mitochondrial quality control to maintain the function of the power-generating organelle. Mitochondrial quality control is particularly important for the maintenance of neural and muscular tissues. Mitophagy is specialized version of the autophagy pathway. Mitophagy delivers damaged mitochondria to lysosomes for degradation. Recently, a series of elegant studies have demonstrated that two Parkinson's disease-associated genes PINK1 and parkin are involved in the… CONTINUE READING
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