Regulation by antibody of lectin-induced lymphocyte proliferation: antibody inhibition of mitogenesis and release of lectin from cell surfaces.

@article{Banks1978RegulationBA,
  title={Regulation by antibody of lectin-induced lymphocyte proliferation: antibody inhibition of mitogenesis and release of lectin from cell surfaces.},
  author={Kristin L Banks and T. C. McGuire and William C. Davis},
  journal={American journal of veterinary research},
  year={1978},
  volume={39 11},
  pages={1784-9}
}
Studies were conducted to determine the ways in which antibody regulates proliferation of lymphocytes stimulated by phytohemagglutinin (PHA) and concanavalin A (ConA). Equine lymphocytes were reacted with PHA or ConA for 1 to 10 hours, washed free of excess lectin, then cultured for 3 days and examined for proliferation and incorporation of [3H]thymidine. Both PHA and ConA induced lymphocytes to proliferate after short incubation periods. This response could be interrupted by the addition of… CONTINUE READING

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