Regulation and role of autophagy in mammalian cells.

@article{Meijer2004RegulationAR,
  title={Regulation and role of autophagy in mammalian cells.},
  author={Alfred J. Meijer and Patrice Codogno},
  journal={The international journal of biochemistry & cell biology},
  year={2004},
  volume={36 12},
  pages={2445-62}
}
The recent period has witnessed progress in the understanding of the lysosomal autophagic pathway. The discovery of a family of genes conserved from yeast to humans, and involved in the formation of autophagosomes, has unraveled new protein-conjugation systems and has shed light on the importance of autophagy in physiology and pathophysiology. The elucidation of the molecular control of autophagy will also lead to a better understanding of the role of autophagy during cell death. As a great… CONTINUE READING
Highly Influential
This paper has highly influenced 11 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 266 extracted citations

Autophagy and cancer

Devrim GÖZÜAÇIK
2014
View 5 Excerpts
Highly Influenced

High glucose induces autophagy in podocytes.

Experimental cell research • 2013
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 180 references

Autophagy. Georgetown, TX: Landes Bioscience

D J.Klionsky
2004
View 10 Excerpts
Highly Influenced

Autophagy in the eukaryotic cell.

Eukaryotic cell • 2002
View 4 Excerpts
Highly Influenced

The autophagosomal–lysosomal compartment in programmed cell death

Cell Death and Differentiation • 2001
View 4 Excerpts
Highly Influenced

Ubiquitin and proteasomes: Molecular dissection of autophagy: two ubiquitin-like systems

Nature Reviews Molecular Cell Biology • 2001
View 14 Excerpts
Highly Influenced

Formation process

T Yoshimori
1999
View 5 Excerpts
Highly Influenced

Delivery of proteins and organelles to the vacuole from the cytoplasm.

Current opinion in cell biology • 1998
View 7 Excerpts
Highly Influenced

Autophagy and related mechanisms of lysosome-mediated protein degradation.

Trends in cell biology • 1994
View 8 Excerpts
Highly Influenced

Regulation of autophagic protein degradation in isolated liver cells

P O.Seglen
1987
View 16 Excerpts
Highly Influenced

Ten years of protein kinase B signalling: a hard Akt to follow.

Trends in biochemical sciences • 2001
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…