Regulation and location of phosphatidylglycerol and phosphatidylinositol synthesis in type II cells isolated from fetal rat lung.

@article{Batenburg1985RegulationAL,
  title={Regulation and location of phosphatidylglycerol and phosphatidylinositol synthesis in type II cells isolated from fetal rat lung.},
  author={Joseph J. Batenburg and Wies Klazinga and Lambert M G van Golde},
  journal={Biochimica et biophysica acta},
  year={1985},
  volume={833 1},
  pages={17-24}
}
myo-Inositol decreases the synthesis of phosphatidylglycerol by type II cells isolated from fetal rat lung. Inositol addition also increases the synthesized amount of surfactant phosphatidylinositol. These observations indicate that at least part of the decreasing effect of inositol on phosphatidylglycerol formation is the result of competition between phosphatidylglycerol and phosphatidylinositol synthesis for a common pool of CDP diacylglycerol. Studies on the subcellular localization of… CONTINUE READING

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