Regulation and inhibition of phospholipase A2.

  title={Regulation and inhibition of phospholipase A2.},
  author={Jes{\'u}s Balsinde and Mar{\'i}a A Balboa and Paul A. Insel and Edward A. Dennis},
  journal={Annual review of pharmacology and toxicology},
In recent years, there has been great interest in the study of phospholipid metabolism in intact cell systems. Such an interest arises mainly from the discovery that cellular membrane phospholipids serve not only in structural roles, but are also reservoirs of preformed second messenger molecules with key roles in cellular signaling. These second messenger molecules are generated by agonist-induced activation and secretion of intracellular and extracellular phospholipases, respectively, i.e… CONTINUE READING
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