Regulation and improvement of triterpene formation in plant cultured cells of Eriobotrya japonica Lindl.

  title={Regulation and improvement of triterpene formation in plant cultured cells of Eriobotrya japonica Lindl.},
  author={Hui-ya Ho and K. Y. Liang and Wen-Chuan Lin and Susumu Kitanaka and Jin-bin Wu},
  journal={Journal of bioscience and bioengineering},
  volume={110 5},

Figures and Tables from this paper

Development of a Cell Suspension Culture System for Promoting Alkaloid and Vinca Alkaloid Biosynthesis Using Endophytic Fungi Isolated from Local Catharanthus roseus

Cell extracts of endophytic fungi—identified as Fusarium solani RN1 and Chaetomium funicola RN3—were found to significantly promote alkaloid accumulation and stimulated the accumulation of a tested bis-indole alkaloids, vinblastine, in C. roseus cell suspension cultures.

A medicinal ginger, Boesenbergia rotunda: from cell suspension cultures to protoplast derived callus.

The results indicated that embryogenic suspension cultures in liquid Murashige and Skoog (MS) medium supplemented with 3% (w/v) sucrose produced the highest growth rate, whereas no promotive effect was seen in the presence of 2,4-dichlorophenoxyacetic acid and those that underwent sonication treatment.

Triterpenes production toLagerstroemia speciosa tissue culture and transformation of oxidosqualene cyclase gene in Nicotiana tabacum

Lagerstroemia speciosa is a deciduous tree found in tropical countries. It has been extensively studied for its different biological activities, particularly for its potency in curing diabetes. The

Anti-hepatocellular carcinoma activity of tormentic acid derived from suspension cells of Eriobotrya japonica (Thunb.) Lindl.

Tormentic acid treatment induced apoptosis in the three hepatocellular carcinoma cell lines evaluated in this study, highlighting the potent anti-cancer activity of TA towards all three of these cell lines.

Caractérisation de l’activité antioxydante des extraits de Eriobotrya japonica L

The antioxidants play a basic role in the elimination of the toxic reactive oxygen species excess. Thus, the exploitation of natural plant molecules will be very beneficial for the human health.

Medicinal plant cell suspension cultures: pharmaceutical applications and high-yielding strategies for the desired secondary metabolites

The scale-up of MPCSC, which could lead to an unlimited supply of pharmaceuticals, including strategies to overcome and solution of the associated challenges, is discussed.

Microbial transformation of corosolic acid by Fusarium equiseti and Gliocladium catenulatum

The growing cultures of Fusarium equiseti CGMCC 3.3658 and Gliocladium catenulatum CGMCC 3.3655 were used for the first time in the structural modification of corosolic acid (1). Four new metabolites

Biotechnological processes to obtain bioactive secondary metabolites from some Mexican medicinal plants

In the scientific literature, procuring the SMt by means of biotechnological processes is described, highlighting the study of five species from Mexican traditional medicine, and the main biological activities are as follows: anti-inflammatory, hepatoprotector, neuroprotector, anxiolytic, antitumoral, antibacterial, and antioxidant.

Biotic and abiotic stress roles in drugs production through in vitro approaches in plants – a review

This is the first review to describe the light factors needed for the SM production, which has favorable role for SMs, and envisage that the researcher can design how to modulate the stress factors in terms of drug improvement from SMs.



Influence of Medium Composition on the Formation of Secondary Compounds in Cell Suspension Cultures of Catharanthus roseus (L.) G. Don

The accumulation of both, alkaloids and polyphenols was stimulated by high concentrations of sucrose and low concentrations of nitrogen containing salts and phosphate, when these minerals were added to the sucrose solution in concentrations commonly used for cell culture media, the accumulation of alkaloid and phenolic compounds was largely suppressed.

Medium and techniques for induction and growth of monocotyledonous and dicotyledonous plant cell cultures

The composition of a medium is described that proved useful to culture callus of a variety of monocotyledonous and dicotylingonous plants and facilitated work with single cells and the enzymatic removal of cell walls in related studies.

Induced accumulation of oleanolic acid and ursolic acid in cell suspension cultures of Uncaria tomentosa

Increasing sucrose from 20 to 50 g l−1 in Uncaria tomentosa cell suspension cultures enhanced ursolic acid and oleanolic acid production from 129 ± 61 to 553 ± 193 μg g−1 cell dry wt. The maximal

Anti-inflammatory and antitumor-promoting effects of the triterpene acids from the leaves of Eriobotrya japonica.

Euscaphic acid exhibited marked antitumor-promoting activity in an in vivo two-stage carcinogenesis test of mouse tumor by using 7,12-dimethylbenz[a]anthracene (DMBA) as an initiator and TPA as a promoter.

Efficiency of liquid culture systems over conventional micropropagation: A progress towards commercialization

Micropropagation in bioreactors for optimal plant production depends upon better understanding of physiological and biochemical responses of plant to the signals of culture microenvironment and an optimization of specific physical and chemical culture conditions to control the morphogenesis of plants in liquid culture systems.