Regulation and function of yeast PAS kinase: a role in the maintenance of cellular integrity.

@article{Grose2009RegulationAF,
  title={Regulation and function of yeast PAS kinase: a role in the maintenance of cellular integrity.},
  author={Julianne H. Grose and Eleanor Sundwall and Jared Rutter},
  journal={Cell cycle},
  year={2009},
  volume={8 12},
  pages={1824-32}
}
The inability to coordinate cellular metabolic processes with the cellular and organismal nutrient environment leads to a variety of disorders, including diabetes and obesity. Nutrient-sensing protein kinases, such as AMPK and mTOR, play a pivotal role in metabolic regulation and are promising therapeutic targets for the treatment of disease. In this Extra View, we describe another member of the nutrient-sensing protein kinase group, PAS kinase, which plays a role in the regulation of glucose… CONTINUE READING

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