Regulation and function of the CXC chemokine ENA-78 in monocytes and its role in disease.

@article{Walz1997RegulationAF,
  title={Regulation and function of the CXC chemokine ENA-78 in monocytes and its role in disease.},
  author={Alfred Walz and P. Schmutz and Christoph M{\"u}ller and Silvia Schnyder-Candrian},
  journal={Journal of leukocyte biology},
  year={1997},
  volume={62 5},
  pages={604-11}
}
Epithelial neutrophil-activating protein 78 (ENA-78) is a member of the CXC chemokines and acts as a potent chemoattractant and activator of neutrophil function. On stimulation in vitro, ENA-78 is highly expressed in many cell types. ENA-78 protein levels are strongly elevated in synovial fluid and blood of patients with rheumatoid arthritis. By in situ hybridization and immunofluorescence staining, ENA-78 has been recognized as a major CXC chemokine expressed in epithelial cells of the… CONTINUE READING