Regulation and function of selenoproteins in human disease.

@article{Bellinger2009RegulationAF,
  title={Regulation and function of selenoproteins in human disease.},
  author={Frederick P. Bellinger and Arjun V Raman and Mariclair A Reeves and Marla J. Berry},
  journal={The Biochemical journal},
  year={2009},
  volume={422 1},
  pages={11-22}
}
Selenoproteins are proteins containing selenium in the form of the 21st amino acid, selenocysteine. Members of this protein family have many diverse functions, but their synthesis is dependent on a common set of cofactors and on dietary selenium. Although the functions of many selenoproteins are unknown, several disorders involving changes in selenoprotein structure, activity or expression have been reported. Selenium deficiency and mutations or polymorphisms in selenoprotein genes and… CONTINUE READING
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